Opill is the first FDA-approved over-the-counter daily oral contraceptive pill in the United States. This progestin-only birth control pill contains 0.075mg of norgestrel and is estrogen-free, making it suitable for most people who can become pregnant. Each package contains 112 tablets providing a 4-month supply (4 packs of 28 days each). Opill works primarily by thickening cervical mucus to help block sperm from reaching the egg, and may also prevent ovulation in some cycles.

When used as directed and taken at the same time every day, Opill is up to 98% effective at preventing pregnancy. The pill starts working 48 hours after you begin taking it, so a barrier method like condoms should be used during the first two days. No prescription or doctor's appointment is required to purchase Opill. It can be purchased with HSA or FSA funds and is now covered by some insurance plans like CVS Caremark for $0 out-of-pocket.

Active Ingredient: Norgestrel 0.075mg per tablet. Inactive Ingredients: colloidal silicon dioxide, D&C Yellow No. 10 aluminum lake, FD&C Yellow No. 6 aluminum lake, lactose monohydrate, magnesium stearate, and povidone. Warnings: Do not use if you have or ever had breast cancer. Stop taking and contact a healthcare professional if you think you are pregnant, experience repeated abnormal vaginal bleeding, develop yellowing of skin or eyes, have severe lower stomach pain, or miss a period after several months of regular periods. Common side effects may include menstrual changes, breakthrough bleeding, headaches, breast tenderness, nausea, and stomach pain. Most side effects are mild and often resolve within the first 3 to 6 months of use.