Seneca Medium 100's Box is a hard-box cigarette offering from Seneca Manufacturing Company (SMC), a federally licensed tobacco manufacturer located in Salamanca, NY on the Seneca Nation of Indians Allegany Territory. The Medium variant is a mid-strength option for smokers who prefer a balanced tobacco experience.

Each box contains 100mm-length cigarettes in the classic hard-box format, offering premium construction at a budget-conscious price point. Seneca cigarettes are widely available through licensed tobacco retailers and distributors across the United States.