Nature Made SAM-e Complete is a dietary supplement providing 400 mg of S-adenosylmethionine (SAM-e) per enteric-coated tablet. SAM-e is a naturally occurring molecule made in the cells of the body and plays an important role in supporting a healthy mood and emotional well-being. Clinical studies show that SAM-e helps restore a healthy mood in as little as 7-14 days when taken daily. This supplement also supports joint comfort, which may naturally deteriorate with physical activity and age, as SAM-e provides a source of sulfur that is a critical component of joint tissue.

The tablets are enteric-coated to protect the active ingredient from stomach acid and ensure optimal absorption. Adults should start by taking 1 tablet per day on an empty stomach at least 30 minutes before a meal. If benefits are not achieved within two weeks, the dose may be gradually increased up to a maximum of 1,600 mg per day under a doctor's supervision. The formula contains no artificial flavors or preservatives and is gluten free.

Supplement Facts per tablet: Protein less than 1g, SAM-e (S-adenosylmethionine) 400 mg. Ingredients: S-adenosylmethionine Tosylate Disulfate, Cellulose Gel, Methacrylic Acid Copolymer, Stearic Acid, Silicon Dioxide, Triethyl Citrate, Magnesium Stearate, Color Added, Mannitol, Sodium Starch Glycolate. People with bipolar depression, pregnant or nursing women, or those taking prescription antidepressant medications should consult their doctor before use.