Excedrin Extra Strength Caplets deliver fast-acting relief from headaches, migraines, sinus headaches, and tension headaches through a clinically proven triple-action formula trusted for over 50 years. Each film-coated caplet contains three active ingredients working together: Acetaminophen (250 mg) as a pain reliever, Aspirin (250 mg, NSAID) as an additional pain reliever, and Caffeine (65 mg) as a pain reliever aid that boosts the efficacy of the other two ingredients. For some users, relief begins in as little as 15 minutes.

In addition to head pain, Excedrin Extra Strength can be used to temporarily relieve toothache, minor arthritis pain, muscular aches, and menstrual cramps. The recommended dose for adults and children 12 years and older is 2 caplets taken with a full glass of water every 6 hours, not to exceed 8 caplets in 24 hours. This Costco value-size 300-count bottle provides an economical supply for households. Inactive ingredients include Benzoic Acid, Carnauba Wax, FD&C Blue 1, Hydroxypropylcellulose, Hypromellose, Light Mineral Oil, Microcrystalline Cellulose, Polysorbate 20, Povidone, Propylene Glycol, Simethicone Emulsion, Sorbitan Monolaurate, Stearic Acid, and Titanium Dioxide.

Do not use if you have ever had an allergic reaction to aspirin or any other pain reliever/fever reducer. Keep out of reach of children. Children and teenagers recovering from chicken pox or flu-like symptoms should not use this product due to the risk of Reye's syndrome. Do not use with other NSAAIDs or products containing acetaminophen.